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Published scientific literature referencing Anavar (Oxandrolone) primarily examines its role as a structurally modified dihydrotestosterone derivative used for analytical and comparative research. Studies often focus on its 2-oxa substitution and 17-alpha alkylation, evaluating how these changes affect androgen receptor affinity, metabolic stability, and oral persistence. Research findings frequently highlight Oxandrolones non-aromatizable nature, making it useful for isolating androgenic signaling without estrogenic interference. Analytical papers also document its consistent chromatographic behavior and reliability as a reference compound in HPLC, LC-MS, and NMR validation studies. Overall, the literature positions Anavar as a stable, well-characterized molecule for structureactivity relationship (SAR) and metabolic pathway investigations rather than broad physiological modeling.